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SAN DIEGO–(BUSINESS WIRE)–
A recent weight loss study shows that when participants know their
genetic make-up, they have greater success losing weight and lowering
their Body Mass Index (BMI). The California Schools VEBA – Pathway
Genomics Corporation study evaluated weight loss results of 179
overweight California school employees. Results at 6 months showed that
when employees took the Pathway Fit® genetic test (of
approximately 100 different genes and their variants related to sugar
and fat metabolism, eating behaviors, best diet, micronutrients, and
other parameters), they had significant weight loss success (some lost
up to 40 pounds) when compared to employees who had previously tried to
lose weight, under similar conditions, without the genetic test.
Both groups of employees worked with a VEBA health coach to help them
develop an exercise and nutrition plan, and all received the same
standard of care. However, the employees who knew and utilized their
genetic-based diets and behaviors obtained greater weight loss (and
other positive effects like decreased blood pressure) when compared with
employees who had health coaching and standard of care only.
A participant in the study describes, “The genetic study helped me
change my overall behaviors and food choices and portion control. The
understanding of my overall genes and physical health has helped me work
more effectively with my VEBA health coach to achieve my weight loss
goals.”
The study—conducted in partnership with the California Schools VEBA
(VEBA), Healthy Adventures Foundation and Pathway Genomics
Corporation—collected interim results in January 2012. Principal
investigator, Wendy Hileman, CEO, Healthy Adventures Foundation
describes, “The findings indicate that when participants have more
information about their genetic predisposition, especially concerning
exercise, eating behaviors, and diets, they have the validation they
need to stick to a tailored program for the long haul, rather than
quitting early on.”
The Pathway Fit® report is a health professional (M.D., D.O.,
N.P.) ordered saliva DNA test, where the participant simply spits in a
plastic tube and sends it to Pathway’s lab to be analyzed. Through the
analysis of genes and their variants (mutations)—which are expressed in
various organs, such as the brain, stomach, gut, muscle, pancreas, and
directly in fat tissue—participants gain insight about how their bodies
process sugars, fats, nutrients and vitamins. This rigorous
scientifically validated information is included in a detailed report
that shows each participant how he or she may respond to a best diet,
certain exercises and eating behaviors, traits such as bitter taste and
caffeine metabolism, and his or her potential response to certain foods
and micronutrients. Recently, there have been a number of double-blinded
studies published showing the utility and positive psychological
responses by patients of genetic testing for weight loss or nutrigenomic
information (eg. Meisel, et al, Obesity, March 2012)
Michael Nova, M.D., Chief Medical Officer, Pathway Genomics, whose team
developed the test says, “The results of this preliminary study
corroborate with the results we’re seeing in other areas of weight loss
and personal nutrition management. When participants gain more knowledge
about themselves, including understanding their metabolism, eating
behaviors and response to exercise, as well as suggestions on the best
ways to reach and maintain a healthy weight given their genetic
predispositions, it helps lead them to make better health decisions and
behavior changes for the long term.”
Because the results were so compelling, VEBA, along with its other study
partners, applied for a grant from the Allen Foundation to help it
continue to roll out the relatively inexpensive Pathway Fit®
test to additional high-risk employees at participating VEBA school
districts.
About the California Schools VEBA
The California Schools VEBA is a trust that offers school districts and
employee organizations buying power and the structure to provide control
over a variety of benefit issues. Benefits trusts continue to positively
influence the quality of care delivered by contracted carriers and their
providers. They also help members attain superior health care choices,
rate stability, portability, affordability and quality for education
employees. Total participation in the trust includes 40 southern
California school districts and associations. The trust serves both
employees and their dependents, totaling more than 89,000 members. For
more information, visit www.vebaonline.com
About Healthy Adventures Foundation
Healthy Adventures Foundation is committed to developing company
wellness programs that educate, inspire, support, and create
opportunities for healthy lifestyle. Its strength lies in the ability to
form collaborative working relationships with diverse groups of
individuals, providing support, resources and expertise in building and
maintaining healthy communities. For more information, visit http://www.healthyadventuresfoundation.org
About Pathway Genomics Corporation
Located in San Diego, California, Pathway Genomics owns and operates an
onsite federally CLIA (Clinical Laboratory Improvement Amendments) and
CAP accredited and California state-licensed laboratory that offers many
high-complexity genetic testing services, including partial gene
sequencing. Using customized and scientifically validated genetic
testing technologies within a controlled and secure environment, Pathway
Genomics conducts genetic testing to generate personalized reports for
health conditions, drug responses, and pregnancy carrier status, as well
as testing for one’s metabolism and exercise response. Pathway’s
services are available through physicians and select health management
organizations, and the Pathway Fit® test is currently sold in
over 34 different countries worldwide. For more information, visit www.pathway.com.
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